Emodin Exerts an Antiapoptotic Effect on Human Chronic Myelocytic Leukemia K562 Cell Lines by Targeting the PTEN/PI3K-AKT Signaling Pathway and Deleting BCR-ABL

The BCR-ABL kinase inhibitor, imatinib mesylate, is the front-line treatment for chronic myeloid leukemia, but the emergence of imatinib resistance has led to the search for alternative drug treatments. There is a pressing need, therefore, to develop and test novel drugs. Natural products including...

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Detalles Bibliográficos
Autores principales: Wang, Chun-Guang, Zhong, Liang, Liu, Yong-Li, Shi, Xue-Jun, Shi, Long-Qin, Zeng, Li, Liu, Bei-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739139/
https://www.ncbi.nlm.nih.gov/pubmed/27698265
http://dx.doi.org/10.1177/1534735416664784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739139/
https://www.ncbi.nlm.nih.gov/pubmed/27698265
http://dx.doi.org/10.1177/1534735416664784

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