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Emodin Exerts an Antiapoptotic Effect on Human Chronic Myelocytic Leukemia K562 Cell Lines by Targeting the PTEN/PI3K-AKT Signaling Pathway and Deleting BCR-ABL
The BCR-ABL kinase inhibitor, imatinib mesylate, is the front-line treatment for chronic myeloid leukemia, but the emergence of imatinib resistance has led to the search for alternative drug treatments. There is a pressing need, therefore, to develop and test novel drugs. Natural products including...
Autores principales: | Wang, Chun-Guang, Zhong, Liang, Liu, Yong-Li, Shi, Xue-Jun, Shi, Long-Qin, Zeng, Li, Liu, Bei-Zhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739139/ https://www.ncbi.nlm.nih.gov/pubmed/27698265 http://dx.doi.org/10.1177/1534735416664784 |
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