Impact of Anthocyanidins on Mitoxantrone-Induced Cytotoxicity and Genotoxicity: An In Vitro and In Vivo Analysis

Hypothesis. Anthocyanins possess well-known biological effects and suppress DNA damage induced by therapeutic topoisomerase poisons. Our study focusses on the modulatory effects of anthocyanidins—malvidin (MAL) and pelargonidin (PEL)—on topoisomerase II poison mitoxantrone (MXT)-induced cytotoxicity...

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Detalles Bibliográficos
Autores principales: Dhivya, Sridaran, Khandelwal, Nidhi, Abraham, Suresh K., Premkumar, Kumpati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739156/
https://www.ncbi.nlm.nih.gov/pubmed/27146128
http://dx.doi.org/10.1177/1534735416628344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739156/
https://www.ncbi.nlm.nih.gov/pubmed/27146128
http://dx.doi.org/10.1177/1534735416628344

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