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Antitumor Effects of Systemic DNAse I and Proteases in an In Vivo Model

Background. Cell-free DNA circulates in cancer patients and induces in vivo cell transformation and cancer progression in susceptible cells. Based on this, we hypothesized that depletion of circulating DNA with DNAse I and a protease mix could have antitumor effects. Study design. The study aimed to...

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Detalles Bibliográficos
Autores principales: Trejo-Becerril, Catalina, Pérez-Cardenas, Enrique, Gutiérrez-Díaz, Blanca, De La Cruz-Sigüenza, Desiree, Taja-Chayeb, Lucía, González-Ballesteros, Mauricio, García-López, Patricia, Chanona, José, Dueñas-González, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739158/
https://www.ncbi.nlm.nih.gov/pubmed/27146129
http://dx.doi.org/10.1177/1534735416631102