Image-based drug screen identifies HDAC inhibitors as novel Golgi disruptors synergizing with JQ1

The Golgi apparatus is increasingly recognized as a major hub for cellular signaling and is involved in numerous pathologies, including neurodegenerative diseases and cancer. The study of Golgi stress-induced signaling pathways relies on the selectivity of the available tool compounds of which curre...

Descripción completa

Detalles Bibliográficos
Autores principales: Gendarme, Mathieu, Baumann, Jan, Ignashkova, Tatiana I., Lindemann, Ralph K., Reiling, Jan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739293/
https://www.ncbi.nlm.nih.gov/pubmed/29074567
http://dx.doi.org/10.1091/mbc.E17-03-0176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739293/
https://www.ncbi.nlm.nih.gov/pubmed/29074567
http://dx.doi.org/10.1091/mbc.E17-03-0176

Ejemplares similares