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Image-based drug screen identifies HDAC inhibitors as novel Golgi disruptors synergizing with JQ1
The Golgi apparatus is increasingly recognized as a major hub for cellular signaling and is involved in numerous pathologies, including neurodegenerative diseases and cancer. The study of Golgi stress-induced signaling pathways relies on the selectivity of the available tool compounds of which curre...
Autores principales: | Gendarme, Mathieu, Baumann, Jan, Ignashkova, Tatiana I., Lindemann, Ralph K., Reiling, Jan H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739293/ https://www.ncbi.nlm.nih.gov/pubmed/29074567 http://dx.doi.org/10.1091/mbc.E17-03-0176 |
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