Activation of ROCK and MLCK tunes regional stress fiber formation and mechanics via preferential myosin light chain phosphorylation

The assembly and mechanics of actomyosin stress fibers (SFs) depend on myosin regulatory light chain (RLC) phosphorylation, which is driven by myosin light chain kinase (MLCK) and Rho-associated kinase (ROCK). Although previous work suggests that MLCK and ROCK control distinct pools of cellular SFs,...

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Detalles Bibliográficos
Autores principales: Kassianidou, Elena, Hughes, Jasmine H., Kumar, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739298/
https://www.ncbi.nlm.nih.gov/pubmed/29046396
http://dx.doi.org/10.1091/mbc.E17-06-0401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739298/
https://www.ncbi.nlm.nih.gov/pubmed/29046396
http://dx.doi.org/10.1091/mbc.E17-06-0401

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