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HID-1 controls formation of large dense core vesicles by influencing cargo sorting and trans-Golgi network acidification
Large dense core vesicles (LDCVs) mediate the regulated release of neuropeptides and peptide hormones. They form at the trans-Golgi network (TGN), where their soluble content aggregates to form a dense core, but the mechanisms controlling biogenesis are still not completely understood. Recent studie...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739301/ https://www.ncbi.nlm.nih.gov/pubmed/29074564 http://dx.doi.org/10.1091/mbc.E17-08-0491 |