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Mechanistic modeling quantifies the influence of tumor growth kinetics on the response to anti-angiogenic treatment

Tumors exploit angiogenesis, the formation of new blood vessels from pre-existing vasculature, in order to obtain nutrients required for continued growth and proliferation. Targeting factors that regulate angiogenesis, including the potent promoter vascular endothelial growth factor (VEGF), is there...

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Detalles Bibliográficos
Autores principales: Gaddy, Thomas D., Wu, Qianhui, Arnheim, Alyssa D., Finley, Stacey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739350/
https://www.ncbi.nlm.nih.gov/pubmed/29267273
http://dx.doi.org/10.1371/journal.pcbi.1005874