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Mechanistic modeling quantifies the influence of tumor growth kinetics on the response to anti-angiogenic treatment
Tumors exploit angiogenesis, the formation of new blood vessels from pre-existing vasculature, in order to obtain nutrients required for continued growth and proliferation. Targeting factors that regulate angiogenesis, including the potent promoter vascular endothelial growth factor (VEGF), is there...
Autores principales: | Gaddy, Thomas D., Wu, Qianhui, Arnheim, Alyssa D., Finley, Stacey D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739350/ https://www.ncbi.nlm.nih.gov/pubmed/29267273 http://dx.doi.org/10.1371/journal.pcbi.1005874 |
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