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Aged interleukin-10(tm1Cgn) chronically inflamed mice have substantially reduced fat mass, metabolic rate, and adipokines
Interleukin 10(tm1Cgn) (IL 10(tm)) mice have been utilized as a model of chronic inflammation and declining health span because of their propensity to develop chronic activation in NFkB pathways, skeletal muscle and cardiac changes, and mitochondrial dysfunction. We hypothesized that older IL 10(tm)...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739384/ https://www.ncbi.nlm.nih.gov/pubmed/29267271 http://dx.doi.org/10.1371/journal.pone.0186811 |