Aged interleukin-10(tm1Cgn) chronically inflamed mice have substantially reduced fat mass, metabolic rate, and adipokines

Interleukin 10(tm1Cgn) (IL 10(tm)) mice have been utilized as a model of chronic inflammation and declining health span because of their propensity to develop chronic activation in NFkB pathways, skeletal muscle and cardiac changes, and mitochondrial dysfunction. We hypothesized that older IL 10(tm)...

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Detalles Bibliográficos
Autores principales: Westbrook, Reyhan M, Yang, Huan Le, Langdon, Jackie M, Roy, Cindy N, Kim, Jin A, Choudhury, Parichoy P, Xue, Qian-Li, di Francesco, Andrea, de Cabo, Rafa, Walston, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739384/
https://www.ncbi.nlm.nih.gov/pubmed/29267271
http://dx.doi.org/10.1371/journal.pone.0186811

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