Maternal obesity in the ewe increases cardiac ventricular expression of glucocorticoid receptors, proinflammatory cytokines and fibrosis in adult male offspring

Obesity during human pregnancy predisposes offspring to obesity and cardiovascular disease in postnatal life. In a sheep model of maternal overnutrition/obesity we have previously reported myocardial inflammation and fibrosis, as well as cardiac dysfunction in late term fetuses, in association with...

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Detalles Bibliográficos
Autores principales: Ghnenis, Adel B., Odhiambo, John F., McCormick, Richard J., Nathanielsz, Peter W., Ford, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739430/
https://www.ncbi.nlm.nih.gov/pubmed/29267325
http://dx.doi.org/10.1371/journal.pone.0189977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739430/
https://www.ncbi.nlm.nih.gov/pubmed/29267325
http://dx.doi.org/10.1371/journal.pone.0189977

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