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SIRT2 gene has a classic SRE element, is a downstream target of serum response factor and is likely activated during serum stimulation
The sirtuin proteins are an evolutionarily conserved family of NAD(+)-dependent deacetylases that regulate various cellular functions. Among the seven sirtuins, SIRT2 is predominantly found in the cytoplasm, and is present in a wide range of tissues. Recent studies indicate that SIRT2 plays an impor...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739444/ https://www.ncbi.nlm.nih.gov/pubmed/29267359 http://dx.doi.org/10.1371/journal.pone.0190011 |