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SIRT2 gene has a classic SRE element, is a downstream target of serum response factor and is likely activated during serum stimulation

The sirtuin proteins are an evolutionarily conserved family of NAD(+)-dependent deacetylases that regulate various cellular functions. Among the seven sirtuins, SIRT2 is predominantly found in the cytoplasm, and is present in a wide range of tissues. Recent studies indicate that SIRT2 plays an impor...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaomin, Azhar, Gohar, Wei, Jeanne Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739444/
https://www.ncbi.nlm.nih.gov/pubmed/29267359
http://dx.doi.org/10.1371/journal.pone.0190011