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Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors

Despite advances in the treatment of HIV infection with ART, elucidating strategies to overcome HIV persistence, including blockade of viral reservoir establishment, maintenance, and expansion, remains a challenge. T cell homeostasis is a major driver of HIV persistence. Cytokines involved in regula...

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Detalles Bibliográficos
Autores principales: Gavegnano, Christina, Brehm, Jessica H., Dupuy, Franck P., Talla, Aarthi, Ribeiro, Susan Pereira, Kulpa, Deanna A., Cameron, Cheryl, Santos, Stephanie, Hurwitz, Selwyn J., Marconi, Vincent C., Routy, Jean-Pierre, Sabbagh, Laurent, Schinazi, Raymond F., Sékaly, Rafick Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739511/
https://www.ncbi.nlm.nih.gov/pubmed/29267399
http://dx.doi.org/10.1371/journal.ppat.1006740