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Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors
Despite advances in the treatment of HIV infection with ART, elucidating strategies to overcome HIV persistence, including blockade of viral reservoir establishment, maintenance, and expansion, remains a challenge. T cell homeostasis is a major driver of HIV persistence. Cytokines involved in regula...
Autores principales: | Gavegnano, Christina, Brehm, Jessica H., Dupuy, Franck P., Talla, Aarthi, Ribeiro, Susan Pereira, Kulpa, Deanna A., Cameron, Cheryl, Santos, Stephanie, Hurwitz, Selwyn J., Marconi, Vincent C., Routy, Jean-Pierre, Sabbagh, Laurent, Schinazi, Raymond F., Sékaly, Rafick Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739511/ https://www.ncbi.nlm.nih.gov/pubmed/29267399 http://dx.doi.org/10.1371/journal.ppat.1006740 |
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