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Computationally-driven identification of antibody epitopes

Understanding where antibodies recognize antigens can help define mechanisms of action and provide insights into progression of immune responses. We investigate the extent to which information about binding specificity implicitly encoded in amino acid sequence can be leveraged to identify antibody e...

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Detalles Bibliográficos
Autores principales: Hua, Casey K, Gacerez, Albert T, Sentman, Charles L, Ackerman, Margaret E, Choi, Yoonjoo, Bailey-Kellogg, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739537/
https://www.ncbi.nlm.nih.gov/pubmed/29199956
http://dx.doi.org/10.7554/eLife.29023