LAST, a c-Myc-inducible long noncoding RNA, cooperates with CNBP to promote CCND1 mRNA stability in human cells

Cyclin D1 is a critical regulator of cell cycle progression and works at the G1 to S-phase transition. Here, we report the isolation and characterization of the novel c-Myc-regulated lncRNA LAST (LncRNA-Assisted Stabilization of Transcripts), which acts as a CCND1 mRNA stabilizer. Mechanistically, L...

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Detalles Bibliográficos
Autores principales: Cao, Limian, Zhang, Pengfei, Li, Jinming, Wu, Mian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739540/
https://www.ncbi.nlm.nih.gov/pubmed/29199958
http://dx.doi.org/10.7554/eLife.30433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739540/
https://www.ncbi.nlm.nih.gov/pubmed/29199958
http://dx.doi.org/10.7554/eLife.30433

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