mSA2 affinity-enhanced biotin-binding CAR T cells for universal tumor targeting

Chimeric antigen receptor T cells (CAR-Ts) are promising cancer therapeutics. However, since cancer cells can lose the CAR-targeted antigen and avoid destruction, targeting multiple antigens with multiple CARs has been proposed. We illustrate here a less cumbersome alternative, anti-tag CARs (AT-CAR...

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Detalles Bibliográficos
Autores principales: Lohmueller, Jason J., Ham, James D., Kvorjak, Michael, Finn, Olivera J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739565/
https://www.ncbi.nlm.nih.gov/pubmed/29296519
http://dx.doi.org/10.1080/2162402X.2017.1368604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739565/
https://www.ncbi.nlm.nih.gov/pubmed/29296519
http://dx.doi.org/10.1080/2162402X.2017.1368604

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