A library-based screening method identifies neoantigen-reactive T cells in peripheral blood prior to relapse of ovarian cancer

Mutated cancer antigens, or neoantigens, represent compelling immunological targets and appear to underlie the success of several forms of immunotherapy. While there are anecdotal reports of neoantigen-specific T cells being present in the peripheral blood and/or tumors of cancer patients, effective...

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Detalles Bibliográficos
Autores principales: Martin, Spencer D., Wick, Darin A., Nielsen, Julie S., Little, Nicole, Holt, Robert A., Nelson, Brad H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739566/
https://www.ncbi.nlm.nih.gov/pubmed/29296522
http://dx.doi.org/10.1080/2162402X.2017.1371895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739566/
https://www.ncbi.nlm.nih.gov/pubmed/29296522
http://dx.doi.org/10.1080/2162402X.2017.1371895

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