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A library-based screening method identifies neoantigen-reactive T cells in peripheral blood prior to relapse of ovarian cancer
Mutated cancer antigens, or neoantigens, represent compelling immunological targets and appear to underlie the success of several forms of immunotherapy. While there are anecdotal reports of neoantigen-specific T cells being present in the peripheral blood and/or tumors of cancer patients, effective...
Autores principales: | Martin, Spencer D., Wick, Darin A., Nielsen, Julie S., Little, Nicole, Holt, Robert A., Nelson, Brad H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739566/ https://www.ncbi.nlm.nih.gov/pubmed/29296522 http://dx.doi.org/10.1080/2162402X.2017.1371895 |
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