Combination of IL-2, rapamycin, DNA methyltransferase and histone deacetylase inhibitors for the expansion of human regulatory T cells

FOXP3(+) regulatory T cell (Treg) based cellular therapies represent promising therapeutic options in autoimmunity, allergy, transplantation and prevention of Graft Versus Host (GVH) Disease. Among human FOXP3-expressing CD4(+)T cells, only the CD45RA(+) naïve Treg (nTreg) subset is suitable for in...

Descripción completa

Detalles Bibliográficos
Autores principales: Miyara, Makoto, Chader, Driss, Burlion, Aude, Goldstein, Jérémie, Sterlin, Delphine, Norol, Françoise, Trebeden-Nègre, Hélène, Claër, Laetitia, Sakaguchi, Shimon, Marodon, Gilles, Amoura, Zahir, Gorochov, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739596/
https://www.ncbi.nlm.nih.gov/pubmed/29285209
http://dx.doi.org/10.18632/oncotarget.10914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739596/
https://www.ncbi.nlm.nih.gov/pubmed/29285209
http://dx.doi.org/10.18632/oncotarget.10914

Ejemplares similares