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Combination of IL-2, rapamycin, DNA methyltransferase and histone deacetylase inhibitors for the expansion of human regulatory T cells

FOXP3(+) regulatory T cell (Treg) based cellular therapies represent promising therapeutic options in autoimmunity, allergy, transplantation and prevention of Graft Versus Host (GVH) Disease. Among human FOXP3-expressing CD4(+)T cells, only the CD45RA(+) naïve Treg (nTreg) subset is suitable for in...

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Detalles Bibliográficos
Autores principales:	Miyara, Makoto, Chader, Driss, Burlion, Aude, Goldstein, Jérémie, Sterlin, Delphine, Norol, Françoise, Trebeden-Nègre, Hélène, Claër, Laetitia, Sakaguchi, Shimon, Marodon, Gilles, Amoura, Zahir, Gorochov, Guy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739596/ https://www.ncbi.nlm.nih.gov/pubmed/29285209 http://dx.doi.org/10.18632/oncotarget.10914

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