Tumor-suppressive effect of S-adenosylmethionine supplementation in a murine model of inflammation-mediated hepatocarcinogenesis is dependent on treatment longevity

Chronic inflammation precedes the majority of hepatocellular carcinoma (HCC) cases. We investigated the chemopreventive potential of S-adenosylmethionine (SAM), an essential donor for all methylation reactions in the cell, at the late precancerous stage of HCC development using the Mdr2-knockout (Md...

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Detalles Bibliográficos
Autores principales: Stoyanov, Evgeniy, Mizrahi, Lina, Olam, Devorah, Schnitzer-Perlman, Temima, Galun, Eithan, Goldenberg, Daniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739599/
https://www.ncbi.nlm.nih.gov/pubmed/29285212
http://dx.doi.org/10.18632/oncotarget.18300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739599/
https://www.ncbi.nlm.nih.gov/pubmed/29285212
http://dx.doi.org/10.18632/oncotarget.18300

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