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Tumor-suppressive effect of S-adenosylmethionine supplementation in a murine model of inflammation-mediated hepatocarcinogenesis is dependent on treatment longevity

Chronic inflammation precedes the majority of hepatocellular carcinoma (HCC) cases. We investigated the chemopreventive potential of S-adenosylmethionine (SAM), an essential donor for all methylation reactions in the cell, at the late precancerous stage of HCC development using the Mdr2-knockout (Md...

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Detalles Bibliográficos
Autores principales:	Stoyanov, Evgeniy, Mizrahi, Lina, Olam, Devorah, Schnitzer-Perlman, Temima, Galun, Eithan, Goldenberg, Daniel S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739599/ https://www.ncbi.nlm.nih.gov/pubmed/29285212 http://dx.doi.org/10.18632/oncotarget.18300

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