Doxycycline inhibits breast cancer EMT and metastasis through PAR-1/NF-κB/miR-17/E-cadherin pathway

Doxycycline displays high efficiency for cancer therapy. However, the molecular mechanism is poorly understood. In our previous study, doxycycline was found to suppress tumor progression by directly targeting proteinase-activated receptor 1 (PAR1). In this study, microRNAs were found to be involved...

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Detalles Bibliográficos
Autores principales: Zhong, Weilong, Chen, Shuang, Qin, Yuan, Zhang, Heng, Wang, Hongzhi, Meng, Jing, Huai, Longcong, Zhang, Qiang, Yin, Tingting, Lei, Yueyang, Han, Jingxia, He, Lingfei, Sun, Bo, Liu, Huijuan, Liu, Yanrong, Zhou, Honggang, Sun, Tao, Yang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739605/
https://www.ncbi.nlm.nih.gov/pubmed/29285218
http://dx.doi.org/10.18632/oncotarget.20418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739605/
https://www.ncbi.nlm.nih.gov/pubmed/29285218
http://dx.doi.org/10.18632/oncotarget.20418

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