Gene editing of the extra domain A positive fibronectin in various tumors, amplified the effects of CRISPR/Cas system on the inhibition of tumor progression

BACKGROUND: The low efficiency of clustered, regularly interspaced, palindromic repeats-associated Cas (CRISPR/Cas) system editing genes in vivo limits the application. A components of the extracellular matrix (ECM), the extra domain A positive fibronectin (EDA+FN), may be a target for CRISPR/Cas sy...

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Detalles Bibliográficos
Autores principales: Lv, Wan-Qi, Wang, Hai-Cheng, Peng, Jing, Wang, Yi-Xiang, Jiang, Jiu-Hui, Li, Cui-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739617/
https://www.ncbi.nlm.nih.gov/pubmed/29285230
http://dx.doi.org/10.18632/oncotarget.21136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739617/
https://www.ncbi.nlm.nih.gov/pubmed/29285230
http://dx.doi.org/10.18632/oncotarget.21136

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