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AIO LQ-0110: a randomized phase II trial comparing oral doxycycline versus local administration of erythromycin as preemptive treatment strategies of panitumumab-mediated skin toxicity in patients with metastatic colorectal cancer

BACKGROUND: Dermatologic toxicities, especially akne-like skin rash, are the most common side-effects associated with anti-epidermal growth factor receptor (EGFR) therapy. Preemptive treatment with oral tetracyclines is recommended as a standard. Topical prophylactic options have thus far not been c...

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Detalles Bibliográficos
Autores principales: Kripp, Melanie, Prasnikar, Nicole, Vehling-Kaiser, Ursula, Quidde, Julia, Al-Batran, Salah-Eddin, Stein, Alexander, Neben, Kai, Hannig, Carla Verena, Tessen, Hans Werner, Trarbach, Tanja, Hinke, Axel, Hofheinz, Ralf-Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739620/
https://www.ncbi.nlm.nih.gov/pubmed/29285233
http://dx.doi.org/10.18632/oncotarget.21249