Targeted next generation sequencing in Chinese colorectal cancer patients guided anti-EGFR treatment and facilitated precision cancer medicine

OBJECTIVE: Colorectal cancer (CRC) patients with both RAS and BRAF wild-type tumors determined by non-next generation sequencing (NGS) testing may still not respond due to the presence of additional mutated genes such as PIK3CA or PTEN. In this study, a broad, hybrid capture-based NGS assay was used...

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Detalles Bibliográficos
Autores principales: Hou, Helei, Liu, Dong, Zhang, Chuantao, Jiang, Yanxia, Lu, Guifang, Zhou, Na, Yang, Xiaonan, Zhang, Xiaoping, Li, Zhuokun, Zhu, Hongmei, Qian, Zhaoyang, Zhang, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739621/
https://www.ncbi.nlm.nih.gov/pubmed/29285234
http://dx.doi.org/10.18632/oncotarget.21349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739621/
https://www.ncbi.nlm.nih.gov/pubmed/29285234
http://dx.doi.org/10.18632/oncotarget.21349

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