Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7

Anthrapyridazones, imino analogues of anthraquinone, constitute a family of compounds with remarkable anti-cancer activity. To date, over 20 derivatives were studied, of which most displayed nanomolar cytotoxicity towards broad spectrum of cancer cells, including breast, prostate and leukemic ones....

Descripción completa

Detalles Bibliográficos
Autores principales: Misiak, Majus, Heldt, Mateusz, Szeligowska, Marlena, Mazzini, Stefania, Scaglioni, Leonardo, Grabe, Grzegorz J., Serocki, Marcin, Lica, Jan, Switalska, Marta, Wietrzyk, Joanna, Beretta, Giovanni L., Perego, Paola, Zietkowski, Dominik, Baginski, Maciej, Borowski, Edward, Skladanowski, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739627/
https://www.ncbi.nlm.nih.gov/pubmed/29285240
http://dx.doi.org/10.18632/oncotarget.21806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739627/
https://www.ncbi.nlm.nih.gov/pubmed/29285240
http://dx.doi.org/10.18632/oncotarget.21806

Ejemplares similares