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Super enhancer associated RAI14 is a new potential biomarker in lung adenocarcinoma

PURPOSE: Tyrosine kinase inhibitors (TKIs) are widely used to treat lung adenocarcinoma patients with EGFR mutations or ALK-fusions. However, patients with wild-type genes or TKIs-resistant mutations lack effective therapeutic targets. Extensive studies reveal that super enhancer (SE), a large cis-r...

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Detalles Bibliográficos
Autores principales: Yuan, Chongze, Hu, Hong, Kuang, Muyu, Chen, Zongwei, Tao, Xiaoting, Fang, Shengjian, Sun, Yihua, Zhang, Yawei, Chen, Haiquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739635/
https://www.ncbi.nlm.nih.gov/pubmed/29285248
http://dx.doi.org/10.18632/oncotarget.22165