Agrin para-secreted by PDGF-activated human hepatic stellate cells promotes hepatocarcinogenesis in vitro and in vivo

Evaluating the process and mechanism of fibrogenesis is essential in hepatocellular carcinoma (HCC), especially in hepatocyte transformation and oncogenic signaling. We evaluated the oncogenic role of agrin secreted by platelet-derived growth factor (PDGF)-induced hepatic stellate cell (HSC) in HCC....

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Detalles Bibliográficos
Autores principales: Lv, Xing, Fang, Cheng, Yin, Ruozhe, Qiao, Bowei, Shang, Runze, Wang, Jianlin, Song, Wenjie, He, Yong, Chen, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739642/
https://www.ncbi.nlm.nih.gov/pubmed/29285255
http://dx.doi.org/10.18632/oncotarget.22186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739642/
https://www.ncbi.nlm.nih.gov/pubmed/29285255
http://dx.doi.org/10.18632/oncotarget.22186

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