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Sensitization of lung cancer cells by altered dimerization of HSP27

Heat shock protein 27 (HSP27, HSPB1) induces resistance to anticancer drugs in various cancer types, including non-small cell lung cancer (NSCLC). Therefore, pharmacological inhibition of HSP27 in NSCLC may be a good strategy for anticancer therapy. Unlike other HSPs such as HSP90 and HSP70, small m...

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Detalles Bibliográficos
Autores principales: Choi, Byeol, Choi, Seul-Ki, Park, You Na, Kwak, Soo-Yeon, Lee, Hwa Jeong, Kwon, Youngjoo, Na, Younghwa, Lee, Yun-Sil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739644/
https://www.ncbi.nlm.nih.gov/pubmed/29285257
http://dx.doi.org/10.18632/oncotarget.22192