Mek activity is required for ErbB2 expression in breast cancer cells detached from the extracellular matrix

Detachment of non-malignant epithelial cells from the extracellullar matrix (ECM) triggers their growth arrest and apoptosis. Conversely, carcinoma cells can grow without adhesion to the ECM. This capacity for anchorage-independent growth is thought to be critical for tumor progression. ErbB2/Her2 o...

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Detalles Bibliográficos
Autores principales: Khan, Iman A., Yoo, Byong H., Rak, Janusz, Rosen, Kirill V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739645/
https://www.ncbi.nlm.nih.gov/pubmed/29285258
http://dx.doi.org/10.18632/oncotarget.22194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739645/
https://www.ncbi.nlm.nih.gov/pubmed/29285258
http://dx.doi.org/10.18632/oncotarget.22194

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