Baicalein suppresses the androgen receptor (AR)-mediated prostate cancer progression via inhibiting the AR N-C dimerization and AR-coactivators interaction

BACKGROUND: Androgen receptor (AR) plays a critical role in prostate cancer (PCa) development and progression. Androgen deprivation therapy with antiandrogens to reduce androgen biosynthesis or prevent androgens from binding to AR are widely used to suppress AR-mediated PCa growth. However, most of...

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Detalles Bibliográficos
Autores principales: Xu, Defeng, Chen, Qiulu, Liu, Yalin, Wen, Xingqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739659/
https://www.ncbi.nlm.nih.gov/pubmed/29285272
http://dx.doi.org/10.18632/oncotarget.22319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739659/
https://www.ncbi.nlm.nih.gov/pubmed/29285272
http://dx.doi.org/10.18632/oncotarget.22319

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