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MutT-related proteins are novel progression and prognostic markers for colorectal cancer

BACKGROUND: MutT-related proteins, including MTH1, MTH2, MTH3 and NUDT5, can effectively degrade 8-oxoGua-containing nucleotides. The MTH1 expression is elevated in many types of human tumors and MTH1 overexpression correlates with the tumor pathological stage and poor prognosis. However, the expres...

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Detalles Bibliográficos
Autores principales: Li, Jin, Yang, Cheng-Cheng, Tian, Xin-Yuan, Li, Yun-Xuan, Cui, Ju, Chen, Zhe, Deng, Zhou-Lu, Chen, Fu-Jun, Hayakawa, Hiroshi, Sekiguchi, Mutsuo, Cai, Jian-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739673/
https://www.ncbi.nlm.nih.gov/pubmed/29285286
http://dx.doi.org/10.18632/oncotarget.22393