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Puerarin attenuates locomotor and cognitive deficits as well as hippocampal neuronal injury through the PI3K/Akt1/GSK-3β signaling pathway in an in vivo model of cerebral ischemia

Ischemic stroke causes irreversible damage to the brain. The hippocampus is a vulnerable region and plays an important role in cognition and locomotor activity. Puerarin is a phytoestrogen that has beneficial effects in treating neurological disorders. How puerarin protects against hippocampal injur...

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Detalles Bibliográficos
Autores principales: Tao, Jinhao, Cui, Yuehua, Duan, Yu, Zhang, Nan, Wang, Congmin, Zhang, Fayong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739733/
https://www.ncbi.nlm.nih.gov/pubmed/29290948
http://dx.doi.org/10.18632/oncotarget.22290