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Puerarin attenuates locomotor and cognitive deficits as well as hippocampal neuronal injury through the PI3K/Akt1/GSK-3β signaling pathway in an in vivo model of cerebral ischemia
Ischemic stroke causes irreversible damage to the brain. The hippocampus is a vulnerable region and plays an important role in cognition and locomotor activity. Puerarin is a phytoestrogen that has beneficial effects in treating neurological disorders. How puerarin protects against hippocampal injur...
Autores principales: | Tao, Jinhao, Cui, Yuehua, Duan, Yu, Zhang, Nan, Wang, Congmin, Zhang, Fayong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739733/ https://www.ncbi.nlm.nih.gov/pubmed/29290948 http://dx.doi.org/10.18632/oncotarget.22290 |
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