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Defined, serum/feeder-free conditions for expansion and drug screening of primary B-acute lymphoblastic leukemia
Functional screening for compounds represents a major hurdle in the development of rational therapeutics for B-acute lymphoblastic leukemia (B-ALL). In addition, using cell lines as valid models for evaluating responses to novel drug therapies raises serious concerns, as cell lines are prone to geno...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739741/ https://www.ncbi.nlm.nih.gov/pubmed/29290956 http://dx.doi.org/10.18632/oncotarget.22466 |