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Inhibition of EZH2 triggers the tumor suppressive miR-29b network in multiple myeloma

Downregulation of tumor suppressor (TS) microRNAs (miRNAs) commonly occurs in human cancer, including multiple myeloma (MM). We previously demonstrated that miR-29b is a relevant TS miRNA, whose expression in MM cells is inhibited by HDAC4-dependent deacetylation. Here, we provide novel insights int...

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Detalles Bibliográficos
Autores principales: Stamato, Maria Angelica, Juli, Giada, Romeo, Enrica, Ronchetti, Domenica, Arbitrio, Mariamena, Caracciolo, Daniele, Neri, Antonino, Tagliaferri, Pierosandro, Tassone, Pierfrancesco, Amodio, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739753/
https://www.ncbi.nlm.nih.gov/pubmed/29290968
http://dx.doi.org/10.18632/oncotarget.22507