Glucose-6-phosphate dehydrogenase and transketolase modulate breast cancer cell metabolic reprogramming and correlate with poor patient outcome

The pentose phosphate pathway is a fundamental metabolic pathway that provides cells with ribose and NADPH required for anabolic reactions — synthesis of nucleotides and fatty acids — and maintenance of intracellular redox homeostasis. It plays a key role in tumor metabolic reprogramming and has bee...

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Detalles Bibliográficos
Autores principales: Benito, Adrián, Polat, Ibrahim H., Noé, Véronique, Ciudad, Carlos J., Marin, Silvia, Cascante, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739767/
https://www.ncbi.nlm.nih.gov/pubmed/29290982
http://dx.doi.org/10.18632/oncotarget.21601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739767/
https://www.ncbi.nlm.nih.gov/pubmed/29290982
http://dx.doi.org/10.18632/oncotarget.21601

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