ICG-001 affects DRP1 activity and ER stress correlative with its anti-proliferative effect

Mitochondria form a highly dynamic network driven by opposing scission and fusion events. DRP1 is an essential modulator of mitochondrial fission and dynamics within mammalian cells. Its fission activity is regulated by posttranslational modifications such as activating phosphorylation at serine 616...

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Detalles Bibliográficos
Autores principales: Zinecker, Heidi, Ouaret, Djamila, Ebner, Daniel, Gaidt, Moritz M., Taylor, Steve, Aulicino, Anna, Jagielowicz, Marta, Hornung, Veit, Simmons, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739772/
https://www.ncbi.nlm.nih.gov/pubmed/29290987
http://dx.doi.org/10.18632/oncotarget.22264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739772/
https://www.ncbi.nlm.nih.gov/pubmed/29290987
http://dx.doi.org/10.18632/oncotarget.22264

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