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Oridonin synergistically enhances JQ1-triggered apoptosis in hepatocellular cancer cells through mitochondrial pathway

Bromodomain and Extra-Terminal Domain (BET) inhibitors, such as JQ1 have emerged as novel drug candidates and are being enthusiastically pursued in clinical trials for the treatment of cancer. However, many solid cancers are resistance to BET inhibitors. To explore methods for improving the therapeu...

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Detalles Bibliográficos
Autores principales: Zhang, Hua-Peng, Li, Gong-Quan, Guo, Wen-Zhi, Chen, Guang-Hui, Tang, Hong-Wei, Yan, Bing, Li, Jie, Zhang, Jia-Kai, Wen, Pei-Hao, Wang, Zhi-Hui, Lv, Jian-Feng, Zhang, Shui-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739777/
https://www.ncbi.nlm.nih.gov/pubmed/29290992
http://dx.doi.org/10.18632/oncotarget.21880