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Oridonin synergistically enhances JQ1-triggered apoptosis in hepatocellular cancer cells through mitochondrial pathway
Bromodomain and Extra-Terminal Domain (BET) inhibitors, such as JQ1 have emerged as novel drug candidates and are being enthusiastically pursued in clinical trials for the treatment of cancer. However, many solid cancers are resistance to BET inhibitors. To explore methods for improving the therapeu...
Autores principales: | Zhang, Hua-Peng, Li, Gong-Quan, Guo, Wen-Zhi, Chen, Guang-Hui, Tang, Hong-Wei, Yan, Bing, Li, Jie, Zhang, Jia-Kai, Wen, Pei-Hao, Wang, Zhi-Hui, Lv, Jian-Feng, Zhang, Shui-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739777/ https://www.ncbi.nlm.nih.gov/pubmed/29290992 http://dx.doi.org/10.18632/oncotarget.21880 |
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