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miR-1271 inhibits ERα expression and confers letrozole resistance in breast cancer

Attenuation of estrogen receptor α (ERα) expression via unknown mechanism(s) is a hallmark of endocrine-resistant breast cancer (BCa) progression. Here, we report that miR-1271 was significantly down-regulated in letrozole-resistant BCa tissues and in letrozole-resistant BCa cells. miR-1271 directly...

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Detalles Bibliográficos
Autores principales: Yu, Tao, Yu, Hai-Ru, Sun, Jia-Yi, Zhao, Zhao, Li, Shuang, Zhang, Xin-Feng, Liao, Zhi-Xuan, Cui, Ming-Ke, Li, Juan, Li, Chan, Zhang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739802/
https://www.ncbi.nlm.nih.gov/pubmed/29291017
http://dx.doi.org/10.18632/oncotarget.22359