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About miRNAs, miRNA seeds, target genes and target pathways

miRNAs are typically repressing gene expression by binding to the 3’ UTR, leading to degradation of the mRNA. This process is dominated by the eight-base seed region of the miRNA. Further, miRNAs are known not only to target genes but also to target significant parts of pathways. A logical line of t...

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Detalles Bibliográficos
Autores principales: Kehl, Tim, Backes, Christina, Kern, Fabian, Fehlmann, Tobias, Ludwig, Nicole, Meese, Eckart, Lenhof, Hans-Peter, Keller, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739805/
https://www.ncbi.nlm.nih.gov/pubmed/29291020
http://dx.doi.org/10.18632/oncotarget.22363