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NFE2L2/NRF2 silencing-inducible miR-206 targets c-MET/EGFR and suppresses BCRP/ABCG2 in cancer cells

The nuclear factor (erythroid-derived 2)-like 2 (NFE2L2/NRF2) plays a critical role in the expression of multiple antioxidant and detoxifying enzymes. Herein, we provide evidence of the molecular links between NRF2 and oncogenic signaling hepatocyte growth factor receptor (HGFR/c-MET) and epidermal...

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Detalles Bibliográficos
Autores principales: Choi, Bo-Hyun, Ryu, Da Young, Ryoo, In-Geun, Kwak, Mi-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739807/
https://www.ncbi.nlm.nih.gov/pubmed/29291022
http://dx.doi.org/10.18632/oncotarget.22513