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Advances and challenges in the detection of transcriptome‐wide protein–RNA interactions

RNA binding proteins (RBPs) play key roles in determining cellular behavior by manipulating the processing of target RNAs. Robust methods are required to detect the numerous binding sites of RBPs across the transcriptome. RNA‐immunoprecipitation followed by sequencing (RIP‐seq) and crosslinking foll...

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Detalles Bibliográficos
Autores principales: Wheeler, Emily C., Van Nostrand, Eric L., Yeo, Gene W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739989/
https://www.ncbi.nlm.nih.gov/pubmed/28853213
http://dx.doi.org/10.1002/wrna.1436