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Genome-wide study of subcutaneous and visceral adipose tissue reveals novel sex-specific adiposity loci in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study

OBJECTIVE: This study aimed to explore genetic mechanisms of regional fat deposition, which is a strong risk factor for metabolic diseases beyond total adiposity. METHODS: A genome-wide association study of 7,757,139 SNPs in 983 Mexican Americans (N(male)=403, N(female)=580) from the Insulin Resista...

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Detalles Bibliográficos
Autores principales: Gao, Chuan, Langefeld, Carl D., Ziegler, Julie T., Taylor, Kent D., Norris, Jill M., Chen, Yii-Der I., Hellwege, Jacklyn N., Guo, Xiuqing, Allison, Matthew A., Speliotes, Elizabeth K., Rotter, Jerome I., Bowden, Donald W., Wagenknecht, Lynne E., Palmer, Nicholette D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740005/
https://www.ncbi.nlm.nih.gov/pubmed/29178545
http://dx.doi.org/10.1002/oby.22074