Genetic fine-mapping and identification of candidate genes and variants for adiposity traits in outbred rats

OBJECTIVE: Obesity is a major risk factor for multiple diseases and is in part heritable, yet the majority of causative genetic variants that drive excessive adiposity remain unknown. Here, we used outbred heterogeneous stock (HS) rats in controlled environmental conditions to fine-map novel genetic...

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Detalles Bibliográficos
Autores principales: Keele, Gregory R., Prokop, Jeremy W., He, Hong, Holl, Katie, Littrell, John, Deal, Aaron, Francic, Sanja, Cui, Leilei, Gatti, Daniel M., Broman, Karl W., Tschannen, Michael, Tsaih, Shirng-Wern, Zagloul, Maie, Kim, Yunjung, Baur, Brittany, Fox, Joseph, Robinson, Melanie, Levy, Shawn, Flister, Michael J., Mott, Richard, Valdar, William, Solberg Woods, Leah C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740008/
https://www.ncbi.nlm.nih.gov/pubmed/29193816
http://dx.doi.org/10.1002/oby.22075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740008/
https://www.ncbi.nlm.nih.gov/pubmed/29193816
http://dx.doi.org/10.1002/oby.22075

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